Research & Publications

Dr Chaban understands the importance of research in order to improve and further the care of infants and children. Please see below for his most recent work: 

Research activities

  • Magnetic Resonance Biomarkers in Neonatal Encephalopathy (MARBLE) Study. January 2014-present
  • Cool Xenon 3: The neuro-protective efficacy of 50% Xenon along with whole body cooling in neonatal encephalopathy, using proton MRS thalamic [NAA] levels and neurodevelopmental outcome at 18 months. Imperial College London, August 2015-present 
  • Magnetic Resonance in Infection-Primed Neonatal Encephalopathy and N-acetyl Cysteine (MARINAC) study. January 2016
  • MSc Project (2011- 2013) Cell death and microglial activation in the newborn piglet following 6h of Isoflurane anaesthesia. University College London, 2011-2013

Publications

  • The efficacy of inhaled nitric oxide treatment in premature infants with acute pulmonary hypertension. D Rallis, A Deierl, G Atreja, B Chaban, J Banerjee. Early Hum Dev. 2018  
  • Surgery increases cell death and induces changes in gene expression compared with anesthesia alone in the developing piglet brain. KD Broad,  G Kawano, I Fierens, E Rocha-Ferreira, M Hristova, M Ezzati, J Rostami, D Alonso-Alconada, B Chaban, J Hassell, B Fleiss, P Gressens, RD Sanders, NJ Robertson. 2017
  • Predictive value of amplitude-integrated EEG (aEEG) after rescue hypothermic neuroprotection for hypoxic ischemic encephalopathy: a meta-analysis. M Chandrasekaran, B Chaban, P Montaldo, S Thayyil. Journal of Perinatology 2017
  • Isoflurane Exposure Induces Cell Death, Microglial Activation and Modifies the Expression of Genes Supporting Neurodevelopment and Cognitive Function in the Male Newborn Piglet Brain. KD Broad, J Hassell, B Fleiss, G Kawano, M Ezzati, E Rocha-Ferreira, PLoS One 11 (11), e0166784 2016
  • Therapeutic hypothermia in neonatal cervical spine injury. P Montaldo, V Oliveira, PJ Lally, B Chaban, G Atreja, O Kirmi, S Thayyil. Archives of Disease in Childhood-Fetal and Neonatal Edition 2016
  • Quantification of ante-mortem hypoxic ischemic brain injury by post-mortem cerebral magnetic resonance imaging in neonatal encephalopathy. P Montaldo, B Chaban, PJ Lally, NJ Sebire, AM Taylor, S Thayyil. European journal of paediatric neurology 19 (6), 665-671 3 2015
  • Magnetic Resonance Biomarkers in Neonatal Encephalopathy (MARBLE): a prospective multicountry study. PJ Lally, S Pauliah, P Montaldo, B Chaban, V Oliveira, A Bainbridge, BMJ open 5 (9), e008912 2 2015
  • Neonatal abdominal radiograph interpretation: a clinical survey. K Styles, E Boot, B Chaban, S Chuang, E Ogundipe. Archives of Disease in Childhood 99 (Suppl 1), A49-A50 2014
  • Determinants of brain injury in a piglet perinatal asphyxia model. KD Broad, G Kawano, A Oliver-Taylor, J Hassell, B Chaban, I Fierens. 
Pediatric Academic Societies 2014

Invited talks

  • Neonatal Ventilation, Search and Rescue Team in Special Situation (SARTISS) conference, Oradea, Romania, October 2014
  • Management of Neonatal Pulmonary Hypertension, Search and Rescue Team in Special Situation (SARTISS) conference, Oradea, Romania, October 2014
  • Neonatal Critical Care Stabilization and Transport, Search and Rescue Team in Special Situation (SARTISS) conference, Oradea, Romania, October 2013
  • Dehydration management and Fluid management, Search and Rescue Team in Special Situation (SARTISS) conference, Oradea, Romania, October 2013

Poster presentations

  • Accuracy of amplitude–integrated EEG in predicting adverse neurodevelopmental outcome after rescue hypothermic neuroprotection for hypoxic ischemic encephalopathy – A systematic review and meta-analysis. M Chandrasekaran, B Chaban, and S Thayyil. Pediatric Academic Society Meeting, San Diego 2015
  • Accuracy of the standard manufacturer software for proton MR spectroscopy post-processing in neonatal encephalopathy at long and short echo times. Fitzpatrick JA, Lally PJ, Pauliah S, Montaldo P, Chaban B, Thayyil S. Pediatric Academic Society Meeting , San Diego 2015
  • Determinants of Brain Injury in a Piglet Perinatal Asphyxia Model. KD Broad, G Kawano, A Oliver-Taylor, J Hassell, B Chaban, X Golay, NJ Robertson. Pediatric Academic Society, Vancouver. May 2014
  • Neonatal abdominal radiograph interpretation: a clinical survey. Boot, K Styles, B Chaban, S Chuang, E Ogundipe. RCPCH Annual Meeting, Birmingham. April 2014
  • Effects of Aquaphor on transepidermal water loss and electrolyte balance in preterm newborn infants. B Chaban, E Ogundipe. 4th Congress of the European Academy of Paediatric Societies EAPS, Turkey, Istanbul, October 2012

Book chapters

  • Asphyxia: Risk Factors, Prevalence and Neurological Impacts, Perinatal infection as risk factor of neonatal encephalopathy. P Montaldo, L Montaldo, B Chaban, S Thayyil. 2014 
  • Search and Rescue Association The Emergency and Disaster Medicine Society in Romania in partnership with University of Oradea – Faculty of Medicine and Pharmacy and the College of Physicians from Romania and Emergency County Hospital Oradea – UPU-SMURD. The Fifth edition, 2013

Get In Touch